Carlos Beltran doubled and belted a solo homer in Tuesday's loss to the Cubs.
Rays optioned RHP Jake Odorizzi to Triple-A Durham.
Charlie Morton threw 5 1/3 scoreless innings to beat the Reds on Tuesday.
Red Sox manager John Farrell said Andrew Bailey remains the team's closer for now, "but there's work to do."
Scott Atchison (groin) is likely to be placed on the disabled list.
Felix Doubront fired eight scoreless innings, guiding the Red Sox to a 3-1 defeat of the Rays in the second half of Tuesday's doubleheader at Fenway Park.
J.J. Hardy went 3-for-4 with a home run as the Orioles beat the Tigers 5-2 on Tuesday.
Jonny Gomes hit a walkoff two-run homer as the Red Sox rallied to beat the Rays on Tuesday night.