1. Marcus Lattimore — South Carolina vs. Kentucky. Lattimore is coming off his worst statistical outing in South Carolina’s 16-13 loss to Auburn, generating 66 yards on 17 carries despite Stephen Garcia’s highly inefficient 9-of-23 passing. Following that performance, Sophomore Connor Shaw will take over the starting job in a move that stands to benefit Lattimore, who’s 124/667/9 ranks first in the SEC and Top Five nationally. Kentucky yields an average of 198.8 rushing yards and 24.6 points per game.
2. Joseph Randle — Oklahoma State vs. Kansas. In addition to scoring consistency and receiving value, Randle is averaging 115.2 yards per game and expected to see an increased workload this week, as Kansas ranks 119th in total defense and 118th against the run. To put those numbers in context, the Jayhawks allowed 604 rushing yards on 50 attempts in their Week 3 loss at Georgia Tech, and yield an average of 545 yards per game. Oklahoma State is rushing eight percent more frequently on offense this season (39.5 Rush/G) as reflected in their year-over-year averages.
3. Cierre Wood — Notre Dame vs. Air Force. Wood posted career numbers last week, accounting for 213 total yards (191 rushing, 22 receiving) in an uncontested 38-10 win over Purdue. Going in to their Week 6 matchup, Notre Dame has won 11 of its last 13 contests against Air Force while averaging 34.9 points per game. Traditionally, Mountain West teams are hotbeds for inflation and we recommend targeting those mismatches whenever possible. Wood is an emerging talent behind an offensive line that’s clicking on all cylinders. Air Force allows an average of 228 rushing and 409.5 total yards per game.
4. Trent Richardson — Alabama vs. Vanderbilt. After five weeks of action, it is becoming apparent that an SEC team will represent the BCS title game for the sixth consecutive season, where Richardson is making his case for Heisman consideration after rushing for 181 yards and two touchdowns in last week’s win at Florida. Currently second in the SEC in rushing behind only Marcus Lattimore, Richardson ranks fourth and third respectively in both yards and scoring. While Vanderbilt (3-1) has put together a strong first quarter, they’re outmatched in every statistical category by Alabama. Richardson should be viewed as a high-end RB1 in all formats.
5. David Wilson — Virginia Tech vs. Miami. Fumbling concerns aside, Wilson leads the ACC with 640 yards in five games and looks to be separating himself as one of the most dynamic playmakers in college football. Unless the passing game improves, Virginia Tech will continue to rely on him going forward — and in his matchup against Miami, who yields an average of 202 rushing yards per game. Wilson provides the type of latitude you want from your RB1 with four, 40-plus yard touchdowns and 60 broken tackles this season.
6. Giovanni Bernard — North Carolina vs. Louisville
7. Ray Graham — Pittsburgh at Rutgers
8. Robert Turbin — Utah State vs. Wyoming
9. Lamar Miller — Miami at Virginia Tech
10. LaMichael James — Oregon vs. California
11. Michael Dyer — Auburn at Arkansas
12. Bernard Pierce — Temple at Ball State
13. Lance Dunbar — North Texas vs. Florida Atlantic
14. Doug Martin — Boise State at Fresno State
15. Eric Stephens — Texas Tech vs. Texas A&M
16. Morgan Williams — Toledo vs. Eastern Michigan
17. Brandon Rutley — San Jose State at Colorado State
18. Treyvon Green — Northwestern vs. Michigan
19. Ronnie Hillman — San Diego State vs TCU
20. Jasmin Hopkins — Northern Illinois vs. Kent State
21. Christine Michael — Texas A&M at Texas Tech
22. Bobby Rainey — Western Kentucky at Middle Tennessee
23. Michael Hayes — Houston vs. East Carolina
24. James Washington — N.C. State vs. Central Michigan
25. Cyrus Gray — Texas A&M at Texas Tech.