Darron Gibson is set to miss significant time away from action for the second time already this season, after injuring his knee while playing for Republic of Ireland in their midweek World Cup qualifier.
After trailing 1-0, Paulinho brought Tottenham back level with a goal just before halftime and Spurs completed the comeback thanks to a Sunderland own goal in the second half to win 1-2.
West Ham United were undone today by own goals and a red card for a nasty challenge by Kevin Nolan and the Hammers were put away by Liverpool 4-1.
Marouane Chamakh scored for the second consecutive game and Crystal Palace earned their second consecutive win, defeating fellow promoted side Cardiff City 2-0.
Robin van Persie was able to work up enough fitness to make the start for Manchester United, but the Red Devils didn't have an answer to penetrate Newcastle's goal and they suffered their second consecutive defeat 0-1.
Daniel Osvaldo scored a fantastic goal to give Southampton a point at home against Manchester City.
Oussama Assaidi stunned Chelsea with a late last minute goal to give Stoke City a 3-2 win.
Leroy Fer was the man for Norwich City today, providing a goal and an assist, and the Canaries were able to keep West Brom out in a 0-2 final.
In a game riddled with own goals Luis Suarez managed to tally a no-doubt intended goal, his 14th of the season, and Liverpool win at home 4-1.
Oscar will face a late fitness test and is considered 50/50 for the match against Stoke City on Saturday.
Brede Hangeland will need surgery to clear up a sciatic nerve issue that is affecting is right leg.
Carl Jenkinson will start his second consecutive Premier League match in place of injured starter Bacary Sagna who is out with a hamstring injury.