Manchester City have named captain Vincent Kompany in the squad to fact West Brom after a two-month absence with a thigh injury.
Mile Jedinak continued his superb fantasy form as Crystal Palace picked up their first win of the season at Everton.
Yaya Toure continues to disappoint as Manchester City drew at home to title rivals Chelsea.
Sunderland's Patrick Van Aanholt continues to impress both on the pitch and in fantasy.
Liverpool have emerged as potential suitors for Manchester City goalkeeper Joe Hart.
Manchester United’s defensive problems deepen as Jonny Evans is replaced after 30 minutes at the King Power Stadium on Sunday while Tyler Blackett was shown red.
Southampton climb into second but the three points at The Liberty came at a cost as James Ward-Prowse and Maya Yoshida are lost to injury.
Everton scored first and last but couldn't put away struggling Crystal Palace at Goodison Park.
Despite goals from Robin van Persie, Angel di Maria and Ander Herrera the Reds lost 5-3 to Leicester City.
Yannick Bolasie scored Palace's third goal in a Man of the Match performance that saw the Eagles pick up an unexpected three points at Goodison Park.
A tight goalless affair between perhaps the two strongest clubs in the league was given a boost by each side's substitutes, with Frank Lampard's goal equalizing an earlier Chelsea strike, and the two powerhouses settled for a 1-1 draw.
Chelsea were given a man advantage after Manchester City defender was sent off in the second half and promptly scored, but a dramatic equalizer by former club legend Frank Lampard left the two sides even in a 1-1 draw.