Daniel Agger is back in contention to face Manchester City after missing out last weekend with a knee injury.
Joe Hart has signed a long-term contract that will keep him at Manchester City until the end of the 2018-19 season.
Radamel Falcao is reportedly nearing full fitness for the first time since arriving at Old Trafford.
Theo Walcott, out with a groin injury since early November, faces a late fitness test in his efforts to return to the line-up for the second time this season.
Stoke's best summer signing looks like he will shake off the hip injury that caused him to be withdrawn early from the 1-1 draw with Crystal Palace.
Marouane Fellaini will miss Manchester United's trip to Aston Villa due to an illness.
Angel Di Maria could be set to return for Manchester United's Week 17 match against Aston Villa after the better part of a month out with a hamstring injury.
Manchester United's season-long defensive injury crisis continues with Marcos Rojo and Chris Smalling replacing Phil Jones and Jonny Evans on the injured list.
West Ham's Diafra Sakho comes highly recommended for Week 17.
Tottenham's Christian Eriksen is one of the top midfield picks for Week 17 as he comes up against Burnley.
QPR's Charlie Austin is tipped to shine against West Brom in Week 17.
It's no surprise to see Aaron Cresswell at the top of the defensive recommendations for Week 17.