Manchester United manager Louis van Gaal confirmed during yesterday’s post-match press conference that Jonny Evans, Antonio Valencia and Luke Shaw missed the friendly victory over Valencia because of injury.
Enner Valencia's rehab is going as planned and David Gold expects him to return in October.
Dimitar Berbatov almost completed a deal to Aston Villa in the transfer window but ended up joining Greek side PAOK.
West Ham United are hopeful Andy Carroll will return to the bench in week five after a prolonged injury absence.
Riyad Mahrez is expected to return in gameweek five after missing the second half of week four with a minor injury.
David de Gea wants a new deal with Manchester United after the transfer to Real Madrid fell through in the last minutes of the transfer deadline.
Tyrone Mings will miss the rest of the season as further tests showed he has ruptured his ACL.
Mark Hughes will be hoping that the international break will provide enough time for full-back Glenn Johnson to recover from injury with a trip to the Emirates in game week five.
An injury that was supposed to be "minor" when it happened in April has turned into September knee surgery and "months" of further recovery.
A training ground hamstring injury means that Crystal Palace midfielder Joe Ledley was not fit enough to start on Thursday as Wales take on Cyprus in a Euro 2016 qualifying game.
Summer signings Max Gradel and Tyrone Mings have been omitted from the Cherries’ 25 man Premier League squad list after the pair suffered serious knee injuries last weekend. Charlie Daniels however - who was also injured during the draw with Leicester – has been included.
Christian Benteke is expected to miss Belgium’s Euro qualifier against Bosnia on Thursday after going for a scan following complaints of tenderness in his thigh.