Alberto Moreno is one of a few doubts among Brendan Rodgers' defenders ahead of this weekend's match with Spurs as he attempts to recover from an ankle injury sustained during Liverpool's loss to Manchester City.
While there weren't many details, Louis Van Gaal said that there was a "light at the end of the tunnel" for long term absentees Antonio Valencia and Marcos Rojo.
Phil Jones suffered a setback in his recovery from an ankle injury during Manchester United's 7-0 U21 league victory of Norwich on Monday.
Jack Colback has been training all week according to Steve McClaren and is available for selection when Newcastle United travel this weekend to take on Chelsea.
Max Gradel has returned to the club and is beginning the early stages of training as he looks to regain his fitness after a lengthy layoff following knee surgery.
Jurgen Klopp revealed that Dejan Lovren will be left out of action this weekend when Liverpool travel to play Aston Villa.
Joe Allen will be "out for a while" according to Liverpool manager Jurgen Klopp, as the midfielder has to recover from a hamstring injury picked up last weekend.
Manchester City will finally see the return of its captain after Vincent Kompany was cleared to make his first appearance of 2016 after a persistent calf injury.
Manchester City have avoided an injury crisis in midfield for at least this weekend after David Silva was passed fit to face Spurs this weekend in a matchup of No. 2 vs. No. 3 at the Etihad.
Chelsea manager Guus Hiddink confirmed Diego Costa suffered a broken nose in training on Thursday and is currently being assessed ahead of the weekend.
Sunderland have terminated the contract of Adam Johnson after he plead guilty to two charges related to sexual activity with a 15-year-old girl.
Despite on-field frustrations, Bojan Krkic has signed a contract extension at Stoke City that will take him through the 2020 season.