Cubs optioned OF Jorge Soler to High-A Daytona, INFs Josh Vitters and Junior Lake to Triple-A Iowa and 3B Christian Villanueva to Double-A Tennessee.
Trevor Cahill was pulled from Wednesday's game against the Marlins after taking a line drive off his leg.
Pablo Sandoval (foot) will begin a minor league rehab assignment Saturday with High-A San Jose.
Angel Pagan (hamstring) will begin a minor league rehab assignment Thursday with High-A San Jose.
Brewers placed OF Norichika Aoki on the paternity leave list.
Padres placed SS Everth Cabrera on the 15-day disabled list, retroactive to June 17, with a mild left hamstring strain.
The Astros have officially agreed to terms with No. 1 overall pick Mark Appel.
Red Sox agreed to terms with first-round pick LHP Trey Ball.
Nationals activated 2B Danny Espinosa from the 15-day disabled list; optioned him to Triple-A Syracuse.
Nationals general manager Mike Rizzo said on 106.7 The Fan on Wednesday that Bryce Harper (knee) will resume baseball activities in "the next day or two."
Chase Utley (oblique) will begin a minor league rehab assignment Wednesday with Double-A Reading.
Ryan Vogelsong had all five pins removed from his surgically-repaired right hand on Tuesday.