Trent Richardson rushed just nine times for 53 yards in Cleveland's Week 16 loss to the Broncos, and departed late with a leg injury.
Devonta Freeman (hip) was limited in Wednesday's practice.
Dez Bryant (knee) was limited at Wednesday's practice.
Jordan Matthews (knee) was limited at Wednesday's practice.
Brandon Marshall (foot) did not practice Wednesday.
Bilal Powell (toe) did not practice Wednesday.
Coach Gary Kubiak confirmed Devontae Booker will start Week 8 against the Chargers if C.J. Anderson (knee) can't play.
Travis Benjamin (knee) is not practicing Wednesday.
Hunter Henry (concussion) is practicing Wednesday.
NFL Network's Mike Garafolo reports C.J. Anderson (knee) is expected to miss "at least a few weeks."
Josh McCown (collarbone) practiced in full Wednesday.
Matt Jones (knee) did not practice Wednesday.