Sofiane Boufal's sensational strike from the left hand side of the top of the box was the difference as Southampton overcame Sunderland in the EFL Cup.
A near full strength Manchester United side overcame a quite rotated Manchester City at Old Trafford in the EFL Cup tonight.
James McCarthy is facing another spell on the sidelines after suffering a hamstring injury during training.
Chuba Akpom could be side-lined until the new year if the latest report from the Independent newspaper proves to be accurate.
Manchester United central defender Eric Bailly is targeting a return to action in December after tests revealed his knee injury is not as bad as originally thought.
With rotation rampant among both sides, it was Liverpool who showed more quality in their depth as a Daniel Sturridge brace saw the Reds knock Tottenham out of the EFL Cup with a 2-1 win.
Chelsea is slowly seeing its defense return to full strength after veterans Branislav Ivanovic and John Terry were passed fit.
Michael Dawson returned to the Hull City starting line up to help them to a close but crucial win in the EFL Cup.
Alex Oxlade-Chamberlain scored a goal on either half of the interval as Arsenal beat Reading 2-0 at the Emirates.
Arsenal returned Carl Jenkinson to the starting line-up against Reading in EFL Cup action on Tuesday but Olivier Giroud was only fit enough for the bench.
Manchester City will be sweating over another injury to star midfielder Kevin De Bruyne after picking up a knock this weekend.
Rumours are circulating that Manchester United manager Joe Mourinho is readying to clear out a large contingent of players in the January transfer window.
Manchester United winger Henrikh Mkhitaryan is available for selection after proving his fitness for the EFL Cup derby with Man City.
Hull City have confirmed via their official Twitter account that their Scottish midfielder Robert Snodgrass will be out of action for up to four weeks.
Chelsea midfielder Nemanja Matic recorded an assist and completed 56 passes in Sunday's victory over Manchester United.