Tyler Lyons earned a win in his major league debut after allowing one run and four hits in seven innings Wednesday against the Padres.
Tim Stauffer pitched 5 2/3 innings in relief Wednesday, allowing one run and striking out seven Cardinals.
Burch Smith lasted just one-plus innings Wednesday and gave up four runs in a loss to the Cardinals.
Yadier Molina had four of the Cardinals' 14 hits in Wednesday's win over the Padres.
Jedd Gyorko went 2-for-4 and hit his fifth homer Wednesday versus the Cardinals.
Brayan Pena went 3-for-5 with an RBI and a run scored in the Tigers' 11-7 victory over the Indians on Wednesday.
Carlos Santana went 2-for-4 with a home run in the loss to the Tigers on Wednesday.
Michael Brantley went 3-for-5 with three RBI in the Indians' loss to the Tigers on Wednesday.
Justin Verlander allowed five runs over five innings but earned the win Wednesday as the Tigers beat the Indians.
Ubaldo Jimenez allowed six runs over four innings in the Indians' loss to the Tigers on Wednesday.
White Sox optioned LHP Donnie Veal to Triple-A Charlotte.
John Danks (shoulder) will be activated from the disabled list to make his season debut Friday against the Marlins.
Clay Buchholz moved to 7-0 on Wednesday after holding the White Sox to one run over seven innings.
Paul Konerko went 2-for-4 with a home run but the White Sox fell to the Red Sox on Wednesday.
Hector Santiago took the loss Wednesday despite allowing just two runs in six innings against the Red Sox.