Gareth McAuley and Jonas Olsson will both likely be missing for Tony Pulis as his Baggies travel to Selhurst Park to battle the manager's former club Crystal Palace.
Gareth McAuley will be available for Week 2 after missing the Baggies' Week 1 loss at the hands of Manchester City.
Gareth McAuley scored a consolation goal as West Brom lost to Arsenal 4-1 at the Emirates on the final day of the season.
Gareth McAuley took a star turn as West Brom notched their second consecutive clean sheet as they stifled Liverpool's attack in Week 34.
Gareth McAuley started his second straight match for West Brom in Week 16 and the Baggies recorded their second straight clean sheet in the 1-0 victory over Aston Villa.
Alan Irvine could be counting the cost on his squad ahead of this weekend after Gareth McAuley became the latest Baggies player to pick up an injury while on international duty.
West Brom's defensive issues may be resolved soon with news that Gareth McAuley could feature as soon as this weekend.
Gareth McAuley could add to Pepe Mel's defensive injury woes as he faces a late fitness check on his calf that will determine if he can face West Ham at the Hawthorns on Saturday.
Gareth McAuley scored the equalizer in injury time as West Brom were able to steal a point late in a 1-1 draw at Fulham.
Steve Clarke, having missed out on Federico Fernandez earlier in the week, has apparently shifted his attention to another South American, Diego Lugano of PSG.
With the chase for Federico Fernandez apparently lost, Steve Clarke has turned his attention to former Wigan defender Andreas Granquist.
With playing time at Napoli hard to come by, West Brom are looking to help Federico Fernandez find some in the Premier League via a loan deal.
The Baggies moved to secure the anchor of their defense, Gareth McAuley, by signing him to a two-year deal with improved terms.