Adam Lallana missed training with the England international squad on Monday as he was deemed not fit to train.
Arsenal had pulled ahead 2-1 when Adam Lallana came up with a well-worked goal from Jay Rodriguez's pass for the final 2-2 score.
Adam Lallana's strike in the 66th minute was enough for Southampton as they held on to the 1-0 lead until the end.
With the January transfer window approaching, Southampton manager Mauricio Pochettino is under no need to sell M Adam Lallana or anyone else.
Adam Lallana and Ricky Lambert grabbed a goal each but Southampton left empty-handed after a 3-2 home defeat by Tottenham.
Adam Lallana played well in both England friendlies this past week and has earned Roy Hodgson's praises.
Fraser Forster, Adam Lallana, and Jay Rodriguez have been given the start in England's friendly against Chile.
Liverpool are linked to a move for Southampton midfielder Adam Lallana.
Southampton XI: Boruc, Clyne, Fonte, Lovren, Shaw, Wanyama, Schneiderlin, Ward-Prowse, Lallana (c), Rodriguez, Lambert
Substitutes: K. Davis (GK), Ramírez, Cork, Lee, Guly, Chambers, Hooiveld.
Adam Lallana has praised Southampton boss Mauricio Pochettino and has credited him with the team's success.
Southampton kept a fourth consecutive clean sheet and won a hard fought game against Swansea.