Mauricio Pochettino has confirmed that both Harry Kane and Mousa Dembele will miss the Europa League second leg clash against Fiorentina at White Hart Lane.
Tottenham suffered a tough loss at the hands of Crystal Palace which eliminated them from the FA Cup and Mousa Dembele picked up a groin injury in the process.
Mousa Dembele will be assessed after limping off towards the end of the comfortable Boxing Day victory over Norwich City at White Hart Lane.
Mauricio Pochettino stated that Mousa Dembele still needs to be assessed to determine the midfielder's availability when Tottenham play Southampton tomorrow.
Mousa Dembele has returned to full training for Tottenham and is expected to be available for selection this weekend when Spurs travel to Southampton.
Mousa Dembele has been ruled out for tomorrow's match as Tottenham host Newcastle United.
Mauricio Pochettino indicated in his press conference ahead of Tottenham's Europa League clash with AS Monaco that Mousa Dembele is "sick" and Harry Kane may be rested.
Mousa Dembele is expected to be available for game week thirteen when Tottenham entertain local rivals West Ham United at White Hart Lane.
Tottenham created some quality chances but could not find the net against Liverpool, but Mousa Dembele helped keep things level in a 0-0 final at White Hart Lane.
Mousa Dembele and Ryan Mason both have a chance to be in the squad for Tottenham when they take on arch rivals Arsenal in the Capitol One Cup on Wednesday.
Mauricio Pochettino has declared Mousa Dembele "doubtful" to be ready for selection this weekend when Tottenham travel to the Stadium of Light.
Tottenham expect to know the full extent of the foot injury suffered by Mousa Dembele within 24 hours after the midfielder was taken off against Everton at White Hart Lane.
Mousa Dembele put an end to his good run of form with a terrible performance against West Ham.
Mousa Dembele is showing signs of life at Tottenham after a frustrating 18 months.