The Indianapolis Colts will enjoy a bye in Week 10 but face the Atlanta Falcons in Week 11, who are fifth among NFL offenses with an average of 402.2 total yards per game.
The Indianapolis defense is 28th among NFL teams in run defense, allowing 124.9 yards per game this season.
The Indianapolis Colts travel to Carolina on Monday to face the Panthers and the NFL's leading rushing attack.
The Indianapolis Colts are 29th in total defense this season, allowing 401.8 total yards per game.
The Indianapolis Colts D/ST will not be a viable Week 6 fantasy option as they host the New England Patriots.
The Indianapolis Colts will face the Houston Texans and struggling quarterback Ryan Mallett in Week 5.
Indianapolis is set to face Tennessee quarterback Marcus Mariota, who was sacked seven times in Week 2 at Cleveland.
The Indianapolis defense will be without two of their top three cornerbacks on Monday night against the New York Jets.
The Indianapolis Colts traded for defensive lineman Billy Winn to boost their depth along the defensive line.
The Indianapolis Star tabbed rookie Henry Anderson as a player who could help contribute on the Colts defensive line after losing DT Arthur Jones to an ankle injury.
The Indianapolis Star labeled the cornerback position as one to watch as the preseason enters Week 3.