Giants coach Ben McAdoo said Eli Manning "absolutely" will play on Saturday against the Bills.
Eli Manning (rest) will not play in Friday's preseason opener.
The Newark Star-Ledger believes it would make sense for the Giants to "push the pace" more this season after the offense has run plenty of no-huddle early on in camp.
Giants WR Dwayne Harris said the team is working on "throwing the ball down the field more."
Eli Manning said the Giants are "definitely" a playoff team this year.
Eli Manning completed 24-of-44 passes for 302 yards and two touchdowns in the Giants' Week 17 loss to the Eagles.
Eli Manning completed 15-of-29 passes for 234 yards, one touchdown, and three interceptions in the Giants' Week 16 loss to the Vikings.
Eli Manning completed 29-of-46 passes for 245 yards, four touchdowns and an interception in New York's 38-35, Week 15 loss to the Panthers.
Eli Manning completed 27-of-31 passes for 337 yards and four touchdowns in the Giants' 31-24, Week 14 win over the Dolphins on Monday night.
Eli Manning is not on the Week 14 injury report.
Eli Manning's Sunday X-ray was to his ankle.
Eli Manning said "everything's good" after undergoing a post-game X-Ray.
Eli Manning completed 18-of-34 passes for 297 yards with one touchdown and one interception and rushed once for two yards in the Giants' Week 13 loss to the Jets.
Eli Manning completed 26-of-51 passes for 321 yards, two touchdowns and three interceptions in the Giants' Week 12 loss to the Redskins.