The Tennessee Titans will face the Carolina Panthers and their league-leading rushing attack in Week 10.
The Tennessee defense could be without cornerback Jason McCourty on Sunday, who is dealing with a groin injury.
The Tennessee Titans will be facing a committee of Houston running backs when they take on the Texans without RB Arian Foster.
The top-ranked pass defense of the Tennessee Titans will face Matt Ryan and the Atlanta Falcons in Week 7.
The Tennessee Titans will face the Miami Dolphins in Week 6, who rank 28th among NFL teams with an average of 314.8 total yards per game this season.
With LeSean McCoy (hamstring) and Karlos Williams (concussion) ruled out for Week 5, the Tennessee Titans will face running backs Anthony Dixon and Dan Herron on Sunday.
The Tennessee Titans will enjoy their bye week in Week 4, with the DC Ray Horton's group having success against opposing quarterbacks through the first three weeks.
The Tennessee Titans will host Andrew Luck and the struggling Indianapolis Colts offense in Week 3.
The Tennessee Titans will face Cleveland quarterback Johnny Manziel on the road in Week 2.
Tennessee LB Brian Orakpo recently discussed the team's desire to apply pressure to rookie quarterback Jameis Winston in Week 1.
The Nashville Tennessean highlighted creating turnovers as a key for the Titans defense as the 2015 season approaches.
The Titans first-team defense gave up 17 points to the Kansas City offense over their first three possessions on Saturday.