The Buffalo defense will face Dallas quarterback Kellen Moore in Week 16.
The Buffalo defense has worked in practice to prepare for the quick pace of Philadelphia's offense.
The Buffalo defense has just 16 sacks this season and four over the last five weeks.
The Buffalo Bills travel to New England in Week 11 to face the NFL's highest-scoring offense.
The Buffalo News noted the defensive line of the Bills as the "face and voice of the frustration and disappointment" of the Buffalo defense through the first half of the season.
The Buffalo Bills will be looking for an improved pass rush as they take on Miami in Week 9.
The Buffalo defense is struggling of late, allowing 68 points over the last two weeks.
Former Bills quarterback Jim Kelly questioned the defensive strategy of the Buffalo defense that has resulted in just nine sacks this season.
The secondary of the Buffalo Bills will receive an upgrade on Sunday as FS Aaron Williams returns to the field.
Vic Carucci of the Buffalo News believes the Bills need to dial up more pressure in Week 4 when they host Eli Manning and the New York Giants.
The Buffalo Bills are expecting quick passes from the Miami offense in Week 3.
Rex Ryan acknowledged the challenge of defending New England tight end Rob Gronkowski as the Buffalo Bills prepare to host the Patriots.
Vic Carucci of the Buffalo News believes that rookie cornerback Ronald Darby could be a liability in Week 1 against Andrew Luck and the Colts.
Buffalo GM Doug Whaley spoke very highly of his defense while talking with the Buffalo News, emphasizing the team's confidence on that side of the ball.