Colts coach Chuck Pagano revealed Monday that Ahmad Bradshaw's injury is a fractured fibula.
Sources tell ESPN's Adam Schefter that initial indications are Ahmad Bradshaw broke his ankle in Sunday night's loss to the Patriots.
Ahmad Bradshaw was on crutches and in a protective boot following Sunday night's loss to the Patriots.
Ahmad Bradshaw was forced from Sunday night's Week 11 game against the Patriots with a lower leg injury.
Ahmad Bradshaw rushed for 50 yards on seven carries in the Colts' Week 9 beatdown of the Giants on Monday night.
Ahmad Bradshaw rushed six times for 35 yards and a touchdown in the Colts' Week 8 loss to the Steelers, adding seven receptions for an additional 52 yards.
Ahmad Bradshaw rushed 10 times for 52 yards with a touchdown and caught three passes for 36 yards with another touchdown in Sunday's Week 7 win over the Bengals.
Ahmad Bradshaw rushed 11 times for 34 yards in Indy's Week 6 win over the Texans, adding three catches for 25 yards and a touchdown.
Ahmad Bradshaw rushed for 68 yards on 15 carries in the Colts' Week 5 win over the Ravens.
Colts OC Pep Hamilton says he has no set rotation at running back.
Ahmad Bradshaw did not practice Wednesday.
Ahmad Bradshaw left the stadium Sunday with a walking boot on his left foot as a precaution.
Ahmad Bradshaw rushed for 32 yards on nine carries and caught two passes for 20 yards and one touchdown in the Colts' Week 4 win over the Titans.
Ahmad Bradshaw turned eight carries into 65 yards and caught 2-of-3 targets for 18 yards and a touchdown in the Colts' Week 3 romp over the Jaguars.