In a radio interview, Bills coach Rex Ryan said, "We're going to run it 50 times if we can."
Bills signed RB LeSean McCoy to a new five-year, $40 million contract that includes $26.5 million guaranteed.
Fox Sports' Mike Garafolo reports the Bills and LeSean McCoy are expected to have a new deal in place before the new league year begins on Tuesday.
A source close to LeSean McCoy told the Philadelphia Inquirer that McCoy is "ready to move on" after initially being "frustrated" over his trade to Buffalo.
A source informed ESPN's Josina Anderson that LeSean McCoy is "frustrated" over being traded to the Bills and is "not going to make it easy, that's for sure."
CBS' Jason La Canfora reports new Bills RB LeSean McCoy is expected to "make noise about wanting an extension," and could even threaten to decline to report to training camp.
Bills acquired RB LeSean McCoy from the Eagles in exchange for LB Kiko Alonso.
Sources tell the Philadelphia Inquirer the Eagles have not approached LeSean McCoy about restructuring his contract.
The Philadelphia Daily News' Paul Domowitch said it is 'not likely' the Eagles want to keep LeSean McCoy at his current $11.95 million cap charge.
LeSean McCoy isn't open to a pay cut.
LeSean McCoy said Sunday he's "sure" he can work something out with the Eagles regarding his contract.
LeSean McCoy rushed 17 times for 99 yards and caught one pass for 15 yards in Sunday's Week 17 win over the Giants.
LeSean McCoy had 22 carries for 88 yards and a touchdown in Saturday's Week 16 loss to Washington.
LeSean McCoy's role in the Eagles' red-zone offense has declined in the last eight games.