Bills coach Rex Ryan reiterated Thursday that he's "cautiously optimistic" LeSean McCoy (hamstring) will be ready for Week 1.
ESPN's Adam Schefter reports LeSean McCoy (hamstring) is expected to be ready for Week 1 against the Colts.
LeSean McCoy has been diagnosed with a left hamstring injury, and will undergo an MRI.
LeSean McCoy departed Tuesday's practice with a left leg injury.
LeSean McCoy (toe) returned to 11-on-11 drills on Thursday.
Coach Rex Ryan said the Bills will "have probably the biggest playbook in the history of man in our running game."
LeSean McCoy has been held out of team drills at Bills camp due to "toe soreness" the last two days.
LeSean McCoy returned to 11-on-11 work at Bills OTAs on Thursday.
Fred Jackson said the Bills want LeSean McCoy "to get 300-plus carries next year."
LeSean McCoy was limited in practice Wednesday because of a sore neck.
Bills RBs coach Anthony Lynn said he would love for LeSean McCoy to lead the league in carries.
Bills coach Rex Ryan says LeSean McCoy and Fred Jackson will both see work on third downs.
In a radio interview, Bills coach Rex Ryan said, "We're going to run it 50 times if we can."
Bills signed RB LeSean McCoy to a new five-year, $40 million contract that includes $26.5 million guaranteed.