A source tells FOX Sports that Danny Woodhead will likely need season-ending surgery on his ankle.
Chargers coach Mike McCoy said Danny Woodhead (ankle) would undergo further testing on Sunday night.
Danny Woodhead was carted off the field after suffering an ankle injury against the Bills.
RB Danny Woodhead has been listed as the starting running back for the Chargers against the Bills Week 3.
The Union-Tribune San Diego suggests Danny Woodhead's role may not change much despite Ryan Mathews' multi-week knee injury.
Danny Woodhead rushed eight times for 32 yards in San Diego's Week 2 win over the Seahawks, adding four catches for an additional 28 yards.
Danny Woodhead managed five yards on six carries in the Chargers' Week 1 loss to the Cardinals.
Danny Woodhead rushed for 16 yards on four carries and caught two passes for 11 yards in Sunday's third preseason game against the 49ers.
Chargers signed RB Danny Woodhead to a two-year contract extension through 2016.
Danny Woodhead rushed for 29 yards on nine carries and caught three passes for ten yards in San Diego's Divisional Round playoff loss.
Danny Woodhead rushed 15 times for 54 yards and a touchdown and caught two passes for 14 yards in the Chargers' Wild Card win.
Danny Woodhead rushed five times for 18 yards and caught seven passes for 42 yards in the Chargers' Week 17 win over Kansas City.
Danny Woodhead rushed eight times for 52 yards in Sunday's Week 16 win over the Raiders, adding three catches for 16 yards.
Danny Woodhead rushed nine times for 29 yards in San Diego's Week 15 win over the Broncos, adding one catch for 13 yards.