The San Diego defense held Miami to 231 total yards and 44 rushing yards in Week 15.
The San Diego defense is 27th among NFL teams in run defense this season, and has given up over 100 rushing yards in 11 of 13 games this season.
The San Diego defense has record just four turnovers since Week 5.
The San Diego defense has been gouged for 405.6 total yards and 29.2 points per game in their last five contests.
San Diego FS Eric Weddle practiced on Friday after missing Wednesday and Thursday's sessions, as is listed as "probable" for Week 12.
San Diego linebacker Manti Te'o (foot) is expected to return to the field in Week 11 when the Chargers host the Kansas City Chiefs.
San Diego CB Jason Verrett is dealing with a groin injury suffered in Monday night's loss to Chicago.
The San Diego defense will look to bounce back from a rough Week 7 performance when they travel to Baltimore on Sunday.
The San Diego defense will face Oakland quarterback Derek Carr on Sunday, who leads the improved Oakland passing game.
The struggling run defense of the San Diego Chargers will face a stiff test in Pittsburgh's Le'Veon Bell on Monday night.
The San Diego defense has allowed just 189.3 passing yards per game through three weeks.
The San Diego Chargers are allowing 4.7 yards per carry on rushing attempts from opposing teams through two weeks.
SS Jimmy Wilson is expected to fill-in at strong safety for San Diego this week, with SS Jahleel Addae listed as doubtful for Sunday's game at Cincinnati.
The San Diego Union-Tribune lists the pass rush of the Chargers as the key to defensive success against Detroit in Week 1.