Colts C Khaled Holmes (ankle) is not expected to play in Week 1.
Colts C Khaled Holmes (ankle) is a "long shot" to be ready for Sunday's opener against the Broncos.
Colts coach Chuck Pagano said the team is "optimistic" C Khaled Holmes (ankle) will be back for Week 1.
Colts C Khaled Holmes could miss multiple weeks with a left ankle sprain.
Colts C Khaled Holmes was forced from Thursday's preseason game against the Jets with a left ankle injury.
Colts GM Ryan Grigson said the team has "plans" for second-year C Khaled Holmes, but insisted the 2013 fourth-round pick would not be handed the starting job.
The Colts plan to hold a camp battle at center between Phil Costa and 2013 fourth-round pick Khaled Holmes.
Colts agreed to terms with No. 121 overall pick C Khaled Holmes on a four-year contract.
Colts selected USC C Khaled Holmes with the No. 121 overall pick.