Gaston Ramirez is expected to be available for Southampton on Saturday after missing time with a heavy illness.
The Saints are missing about half a dozen players but the return of Ramirez should provide some sort of relief. Ramirez probably won't start the game but don't be surprised if he is the first player off the bench.
Morgan Schneiderlin is unavailable for selection for Saturday's game against Manchester City with a groin injury.
Schneiderlin's absence just adds to the Saints' lengthy injury report. With so many players missing, don't be surprised to see Manchester City win in a comfortable fashion. James Ward-Prowse will likely start in Schneiderlin's place once again.
Southampton midfielder Victor Wanyama has been ruled out for this week's game and could face a lengthy absence with a hairline fracture in his leg.
Wanyama suffered the injury during the Saints' midweek game against Aston Villa and was subbed out. There is no time table for his return but he will likely miss more than just this game. Wanyama has been a big part of the Saints run this year and will be missed. Jack Cork will start in his place. Cork didn't play well last game but he attributed his poor play to rustiness. He played well for the Saints last season and fans will expect to see him regain his form as he gets more playing time during Wanyama's absence.
Southampton right-back Nathaniel Clyne has been ruled out of Southampton's match against Manchester City because of a hamstring injury.
Clyne left the midweek match with the injury and was replaced by Jose Fonte. With Fonte likely returning to the starting lineup in his regular center-back spot, Maya Yoshida or Calum Chambers will likely start at right-back.
Jose Fonte is expected to return to the starting lineup after coming off the bench last weekend.
Fonte came off the bench last time out because he was recovering from an injury and wasn't fit enough for 90 minutes of action. He is not an advised play against Manchester City, who are currently in great form. If you want a Saints player, I would go with Dejan Lovren, who is better at producing fantasy points without a clean sheet.
Oscar will face a late fitness test and is considered 50/50 for the match against Stoke City on Saturday.
If Oscar can't go because of the ankle, Eden Hazard, Juan Mata, and one of Willian or Andre Schurrle will likely start for Chelsea. That is not a guarantee because this is Chelsea's third match in seven days and Jose Mourinho could choose to rest some players. The Blues need to be careful as Stoke have shown solid defense when playing at home.
Brede Hangeland will need surgery to clear up a sciatic nerve issue that is affecting is right leg.
New manager Rene Muelensteen will likely continue with Aaron Hughes and Phillipe Senderos in central defence.
Toni Luna has been ruled out for Aston Villa's game against Fulham on Sunday with a minor groin injury.
Luna missed a few games due to a hamstring injury but returned for Villa's last match against Sunderland and played the entire match. In his absence, Ciaran Clark, Nathan Baker, Ron Vlaar, and Leandro Bacuna are expected to start but Matthew Lowton can also contend for a starting spot.