Crystal Palace's 1-0 defeat by Tottenham proved costly as influential defender Mamadou Sakho was forced off midway through the second half.
Mamadou Sakho is poised to return against Tottenham on Wednesday evening as James Tomkins is set for a spell on the sidelines.
Crystal Palace will face its toughest stretch of the season yet, but a crop of injury returnees are sure to help the cause.
Crystal Palace picked up another needed point on Saturday as they rallied from a two-goal deficit to draw 2-2 with Leicester City at Selhurst Park.
Crystal Palace has received a major boost with the return of winter signing Patrick van Aanholt following an ankle injury.
Andros Townsend thinks he’ll "definitely be fit for Saturday" after leaving Selhurst Park on crutches last night.
Wilfried Zaha assisted on two Crystal Palace goals as the Eagles beat Arsenal 3-0 at Selhurst Park.
Crystal Palace manager Sam Allardyce doesn't expect midfielder Yohan Cabaye to miss too much time with a calf injury.
Sam Allardyce lamented yet another addition to Crystal Palace's growing injury list with Yohan Cabaye ruled out.
Crystal Palace will be without centre-backs Scott Dann and James Tomkins for the midweek trip to Southampton.
Crystal Palace pulled of its biggest win of the season with a stunning upset of Chelsea in a 2-1 victory at Stamford Bridge.
Southampton manager Claude Puel is expected to continue his January interest in Mamadou Sakho into the summer.
It wasn't a banner day for the attack at Selhurst Park but they kept another clean sheet and made it work for three points against Watford.
Crystal Palace made it back-to-back wins at the Hawthorns this afternoon to climb out of the bottom three, but the victory came at a cost as Patrick van Aanholt was forced off through injury.
Wilfried Zaha scored the opener and Andros Townsend doubled it up as Crystal Palace won their second match on the bounce.