Both Arouna Kone and Darron Gibson are doubts to make another appearance this season according to Everton boss Roberto Martinez.
Roberto Martinez updated the timetable for Leighton Baines' return from a toe injury, stating he thinks the left back will be out for another 3-4 weeks.
It's been since 1992 that Everton won at Old Trafford but former United goalkeeper Tim Howard got the clean sheet and the win as the Toffees broke through in Manchester.
Bryan Oviedo scored his second goal in as many starts since filling in for the injured Leighton Baines, and it was the only goal of a tightly fought game with Manchester United.
Everton boss Roberto Martinez gave an update on Leighton Baines' status in his recent press conference, stating the left back was making good progress with his toe injury, but could not provide a timetable for his return, going so far as to say Baines may not be ready until the New Year.
Gerard Deulofeu scored what would prove to be the winning goal in Everton's 4-0 destruction of Stoke City in Week 13.
According to Everton's official Twitter page, "(Roberto) Martinez says he won't rush Antolin Alcaraz after he returned to action in a behind-closed-doors friendly this week."
Roberto Martinez attempted to offer a bit more clarity on Leighton Baines' toe injury, stating that the left back could be held out of action from a period anywhere between ten days to six weeks.
West Ham are preparing an offer for Everton striker Nikica Jelavic.
Leighton Baines is facing a month out with a fractured toe, suffered during Everton's pulsating 3-3 draw with Liverpool on Saturday.
After a two game drought without a goal, Romelu Lukaku returned to his scoring ways with a pair of goals to pull Everton from behind and take the lead against rivals Liverpool, but a late equalizer by the Reds ended the affair in a 3-3 draw.
Antolin Alcaraz, nursing a hernia injury since being signed by Everton over the summer, has finally returned to fitness and is available for selection, but manager Roberto Martinez stated he will not start the weekend against rivals Liverpool.
Looking the clear favorites to take three points today, Everton were disappointed to finish with a 0-0 draw at home to Crystal Palace.
Arouna Kone injured his knee against Hull City which will keep him out for the majority, if not all of the season.
Romelu Lukaku, who was an injury doubt after coming off worse in his clash with Hugo Lloris, trained on Tuesday and was passed fully fit.