Stephen Ireland will be held out of the Stoke City squad for Week 3 as he nurses a rib injury back to health.
A groin injury is set to keep US international Geoff Cameron out of the Stoke City squad for the Week 3 trip to Manchester City.
Major transfer acquisition Joleon Lescott is still not ready for action as West Brom travel to Swansea in Week 3.
Sebastien Pocognoli has had a strong start to his West Brom career but he won't get to continue it in Week 3 with the right back out with a thigh injury.
Manchester United's defense continues to have injury issues as Chris Smalling will miss Week 3 against Burnley after limping off in Week 2 at Sunderland.
Jonny Evans returned to active duty against MK Dons this week and will likely eye a return to league action this weekend against Burnley
Martin Skrtel joins a growing list of injured Liverpool defenders as he will need to be assessed over the next 48 hours before Brendan Rodgers can decide on his availability against Tottenham.
Brendan Rodgers has revealed that Adam Lallana will be in the squad for Liverpool when they travel to White Hart Lane to face Tottenham this weekend.
Mauricio Pochettino's winning start as Tottenham manager continued as they thrashed AEL Limassol to clinch their place in the Europa League group stage.
Arsenal's Alexis Sanchez can be picked up for a bargain price for the match against Leicester.
Manchester United's Robin van Persie can open his goal account for the season against Burnley in Week 3.
Nik Argiropoulos believes Stevan Jovetic will continue his excellent start to the season against Stoke in Week 3.
West Ham's Cheikhou Kouyate is showing signs of being a solid points scorer in the Yahoo fantasy format
Dusan Tadic can continue his good fantasy form as Southampton travel to Upton Park to face West Ham in Week 3.
Nik Argiropoulos is tipping Yaya Toure to break out of his fantasy slump against Stoke in Week 3.