Graziano Pelle could lose his starting job after a series of horrible performances.
Toby Alderweireld should be available for Southampton in week 28.
Ryan Bertrand returned from his three-match ban to produce six fantasy points in the Yahoo! game.
Sadio Mane was benched against Liverpool this weekend for being half an hour late to the team meeting on Sunday.
Dusan Tadic and Sadio Mane were left on the bench to start the match against Liverpool today.
Toby Alderweireld has been ruled out for gameweek 26 with his continued hamstring problem.
Matt Targett is probable for gameweek 26 after recovering from a concussion.
Shane Long and Morgan Schneiderlin face late tests ahead of game-week 26, but both are probable to feature unless they suffer any adverse reaction from Friday's training.
Morgan Schneiderlin returned to training on Thursday and is probable to play against Liverpool this weekend.
Nathaniel Clyne has continued his impressive season, finishing with 16 fantasy points this week and making the Best XI once again.
Morgan Schneiderlin returned to the squad in week 23 but started on the bench as he was lacking fitness.
Toby Alderweireld is still a week away from returning and will miss Southampton's match against West Ham United.
Matt Targett will miss the midweek clash with West Ham United due to a slight concussion he picked up over the weekend.
Graziano Pelle is amid his worst scoring drought as a member of Southampton, lowering his fantasy price to under 6m in Yahoo, but he should still be a consideration for fantasy XI's when Southampton host West Ham United.
Maya Yoshida shifted to left-back during Southampton's match against QPR yesterday and was successful in the role.