Liam Bridcutt has failed to recover from injury in time to face champions Chelsea at Stamford Bridge on the final day of the 2014/15 British Premier League season.
Wes Brown will miss the last match of the season due to a knee injury.
Jordi Gomez has been ruled out for the last match of the season with a knee injury.
Danny Graham is a doubt for gameweek 38 with an ankle injury.
Costel Pantilimon will not be risked in gameweek 38 with a knee injury.
Sebastian Larsson will be assessed ahead of the final game at Stamford Bridge but Dick Advocaat will take no risks after a hard fought draw against Arsenal on Wednesday was enough to secure their place in the top flight for another season.
Sunderland are again safe for another season in the Premier League after holding Arsenal scoreless at the Emirates.
Sunderland rode a Costel Pantilimon clean sheet to a nil-nil draw that saw them inch slightly closer to safety and another season in the Premier League.
Sunderland skipper John O’Shea is facing a race against time to feature in his side’s crucial battle of the basement clash with Leicester after struggling to shake off injury.
Sunderland grabbed three vital points today on the back of two deflected goals to move out of the relegation zone for now in a 0-2 win over Everton.
John O’Shea ended his record of being the only Premier League player to have participated in every single minute of every game this season after failing to recover from a couple of early knocks against Southampton.
Jordi Gomez scored twice - both times off of penalties - to help Sunderland beat Southampton 2-1.
Scottish international Steven Fletcher is hoping to return before the end of the season after aggravating an ankle injury in training.
Connor Wickham scored in the first minute but Sunderland were dominated for the rest of the match and dropped into the relegation zone after having to settle for a 1-1 draw.
Sunderland will be without Seb Larsson for the visit of Crystal Palace in Week 32.