Enner Valencia could miss up to three months with a knee and ankle injury.
West Ham lost their final pre-season friendly to Werder Bremen by a score of 2-1.
Enner Valencia has suffered a serious injury to his knee and and ankle during the club's Europa League match on Thursday.
Joey O'Brien picked up an injury during West Ham's Europa League match today.
Enner Valencia injured his knee in the West Ham's match against Astra Giurgiu today and will have a scan on Friday.
James Collins was sent off in West Ham's 2-2 Europa League draw against Astra Giurgiu after receiving a harsh second yellow.
Winston Reid will miss West Ham's Europa League match against Astra.
Pedro Obiang will miss West Ham's match against Astra due to a minor injury.
Dimitri Payet was credited with the goal that gave West Ham a 1-0 win over Norwich City earlier today.
Diafra Sakho failed to capitalize on his chances in West Ham's 0-0 draw against Charlton Athletic.
Alex Song has returned to Barcelona – for the moment at least – after the Cameroonian midfielder had surgery to remove a piece of floating bone from his ankle.
West Ham United lost their aggregate lead, went down to ten men and needed a penalty shootout in order to squeak by Maltese side Birkirkara, 1-0 (winning penalties 5-3)
Dimitri Payet stole the show in West Ham United's 3-2 win over Southend at Roots Hall today.
James Tomkins scored a last minute goal from a Mauro Zarate cross to give West Ham a 1-0 opening leg win over Birkirkara in the Europa League on Thursday.
The BBC are reporting via Twitter that Stewart Downing's move to childhood club Middlesbrough has been completed.