Jurgen Klopp stated in his press conference ahead of Liverpool's match against Swansea City that he is "unsure" on the possible involvement of Philippe Coutinho.
Everton manager Roberto Martinez said he will wait as long as he can to determine whether Leighton Baines is match ready to face Bournemouth this weekend.
Daniel Sturridge has been sent to have a scan on his foot after having an injury setback during training.
Aaron Ramsey returned to first team action as a second half substitute against Dinamo Zagreb on Tuesday.
Phillip Wollscheid will face a late fitness test after the defender missed training on Thursday. Manager Mark Hughes confirmed. "His pelvis was a little sore," although he remained hopeful that the German could take part in Fridays’ session.
Remi Garde has confirmed that Jack Grealish will not be involved this weekend after the 20-year-old was seen partying just hours after the defeat to Everton.
Alexis Sanchez continues to be the main focus of Arsenal attention after Arsene Wenger alluded to the fact that his Chilean winger would be checked on Thursday having felt a slight problem in his hamstring.
Manchester City could be without goalkeeper Joe Hart after the England starter left the club's 1-0 Champions League loss to Juventus with a hamstring injury.
Manchester City have been dealt another blow along the back-line as manager Manuel Pellegrini confirmed defender Vincent Kompany will need at least two more weeks to recover from a calf injury.
Sunderland could be boosted by the fitness of two key attackers for the weekend match against Stoke City as Jermain Defoe and Fabio Borini are expected to be available.
Everton are slowly returning to full fitness from their injury woes as manager Roberto Martinez confirmed that Muhamed Besic is fully fit and ready to return from a hamstring injury.
Christian Benteke, who was somewhat of a surprise omission from Jurgen Klopp's starting XI in Liverpool's win over Manchester City this past weekend, is in contention to face Bordeaux in Europa League action on Wednesday.
Jurgen Klopp revealed that center back Martin Skrtel is a doubt for Liverpool's Europa League tie with Bordeaux on Thursday due to illness.
Karl Darlow is back to full fitness after starting Newcastle United's U-21 match against West Bromwich Albion's U-21's on Monday.
Mauricio Pochettino is keeping regular full backs Kyle Walker and Danny Rose out of the squad for Tottenham's Europa League tie with Qarabag, meaning Ben Davies and seldom used Kieran Trippier should get starts on Thursday.