Sean O'Sullivan was scratched from his scheduled start Thursday for Triple-A Pawtucket.
Joe Kelly (groin) will throw a bullpen session Friday.
The Red Sox could call up pitching prospect Aaron Wilkerson to make his major league debut on Sunday against the Angels.
Hanley Ramirez (side) hopes to play on Friday.
Hanley Ramirez is considered day-to-day with an injury to his right side.
David Price struck out 10 batters, but took the loss after allowing four runs in 6 1/3 innings Wednesday against the Rays.
Hanley Ramirez exited Wednesday's game against the Rays in the eighth inning with an apparent injury.
Red Sox OF prospect Andrew Benintendi matched a career-high with four hits Tuesday in Double-A Portland's loss to Trenton.
Chris Young (hamstring) underwent an MRI on Monday which revealed "a little bit more injury" than the initial evaluation.
Xander Bogaerts is back in Wednesday's lineup against the Rays.
Travis Shaw went 3-for-5 with a home run and five RBI in Tuesday's 8-2 win over the Rays.
Jackie Bradley Jr. went 2-for-5 with an RBI double, a stolen base and two runs scored Tuesday against the Rays.
Hanley Ramirez reached base five times Tuesday, collecting an RBI and a run scored in a win over the Rays.
Rick Porcello limited the Rays to one run over six innings, striking out eight, in a win Tuesday.
Red Sox manager John Farrell said during a radio appearance on WEEI that Xander Bogaerts will get the day off off Tuesday versus the Rays.