Tsuyoshi Wada (groin) will make a minor league rehab start with Triple-A Iowa on Friday.
Jason Hammel was charged with four runs over 6 1/3 frames in Friday's loss to the Padres.
Kris Bryant went 0-for-4 with three strikeouts in his major league debut Friday.
Cubs activated OF Chris Denorfia from the 15-day disabled list.
Cubs placed RHP Neil Ramirez on the 15-day disabled list, retroactive to April 16, with right shoulder inflammation.
Cubs placed 3B Mike Olt on the 15-day disabled list, retroactive to April 15, with a hairline fracture in his right wrist.
Cubs purchased the contract of 3B Kris Bryant from Triple-A Iowa.
According to Jesse Rogers of ESPN Chicago, Mike Olt (wrist) will be placed on the disabled list to create room on the big league roster for Kris Bryant.
Jesse Rogers of ESPN Chicago reports that top prospect third baseman Kris Bryant will be called up by the Cubs on Friday.
Neil Ramirez will undergo an MRI on his right shoulder.
Neil Ramirez left Wednesday's game against the Reds with right shoulder discomfort.
Travis Wood earned his first win of the season, shutting out the Reds over seven innings as the Cubs on 5-0 on Wednesday.
Anthony Rizzo's two-run home run was all the offense the Cubs needed to take down the Reds on Wednesday.
Neil Ramirez left Wednesday's game against the Reds with an undisclosed injury.
Mike Olt (wrist) is out of the Cubs' starting lineup again on Wednesday against the Reds.