Willson Contreras clubbed his 11th home run as the Cubs fell to the Cardinals on Saturday afternoon in Chicago.
Jason Hammel was clobbered in Saturday's loss to the Cardinals, surrendering six runs on six hits over his 2 1/3 innings.
Jorge Soler returned to the Cubs starting lineup on Saturday.
Jorge Soler (side) struck out as a pinch hitter in Friday afternoon's victory over the Cardinals.
Jake Arrieta dominated the Cardinals on Friday, striking out 10 across seven shutout innings in a 5-0 victory.
Anthony Rizzo went 3-for-5 with an RBI double and run scored in Friday's win over the Cardinals.
Cubs activated RHP Pedro Strop from the 15-day disabled list.
Willson Contreras is not in the Cubs' lineup Friday.
John Lackey held the Reds to two runs in seven innings as the Cubs won 9-2 on Wednesday.
Ben Zobrist went 3-for-4 with an RBI and two runs scored in Wednesday's win over the Reds.
Dexter Fowler hit a solo home run and scored three times in a win over the Reds on Wednesday.
Kyle Hendricks will be pushed back from a scheduled Saturday outing against the Cardinals to start against the Pirates on Monday
Jon Lester was brilliant again Tuesday, yielding a lone run over seven innings in a 6-1 win over the Reds.
Kris Bryant went 3-for-5 with two doubles, an RBI and a run scored in Tuesday's win over the Reds.
Dexter Fowler went 2-for-3 with an RBI single, a stolen base and two runs scored Tuesday against the Reds.