Zach McAllister yielded two runs in six innings Monday in a no-decision against the Astros.
Ryan Raburn is expected to undergo an MRI on his ailing left knee.
The Indians will skip T.J. House's next turn in the rotation following last week's rainout.
Michael Brantley went 2-for-4 with a homer and two RBI in Saturday's loss to the Tigers.
Danny Salazar gave up three earned runs in 5 2/3 innings Saturday in a no-decision at Detroit.
Ryan Raburn left Saturday's game versus the Tigers with a hyperextended left knee.
Ryan Raburn blasted his fourth home run of the season on Friday as the Indians dropped the opener of their three-game weekend series to the Tigers.
Lonnie Chisenhall went 2-for-4 and drove home a run in Friday's loss to the Tigers.
Carlos Carrasco gave up four runs on seven hits over 6 1/3 innings in a losing effort against the Tigers on Friday.
T.J. House allowed four hits over seven innings as the Indians beat the Twins 2-0 in the second game of Thursday's doubleheader.
Carlos Santana homered in both games of Thursday's doubleheader against the Twins.
Corey Kluber fell just a bit short of his second straight complete game Thursday, allowing two runs in 8 1/3 innings against the Twins.
Yan Gomes homered, doubled and knocked in three runs Thursday against the Twins.
Mike Aviles (concussion) is available on Thursday.
Wednesday night's game between the Twins and Indians has been postponed due to storms in Cleveland.