Brandon Crawford (fingers) is not in Wednesday's lineup against the Padres.
The Astros have officially agreed to terms with No. 1 overall pick Mark Appel.
Orioles manager Buck Showalter said Wednesday that Jake Arrieta will join the starting rotation with Triple-A Norfolk.
Red Sox agreed to terms with first-round pick LHP Trey Ball.
The Phillies have promoted prospect third baseman Maikel Franco to Double-A Reading.
Orioles manager Buck Showalter said that Nolan Reimold (hamstring) felt good after his first rehab game with Double-A Bowie on Tuesday.
Jaff Decker will be recalled from Triple-A Tucson on Wednesday.
Jon Heyman of CBS Sports reports that people who have spoken with MLB investigators feel it's likely that "at least some" suspensions will be issued in the Biogenesis case.
Nationals activated 2B Danny Espinosa from the 15-day disabled list; optioned him to Triple-A Syracuse.
Nationals general manager Mike Rizzo said on 106.7 The Fan on Wednesday that Bryce Harper (knee) will resume baseball activities in "the next day or two."
Bud Norris told FOX Sports' Jon Paul Morosi that it would be a "dream come true" to pitch for the Giants.
Brian Roberts (knee, hamstring) began doing sprints Tuesday.
Matt Wieters is not in the Orioles' lineup for Wednesday's game against the Tigers.
Hanley Ramirez will serve as the designated hitter in the first game of Wednesday's doubleheader against the Yankees.
Torii Hunter is not in Wednesday's lineup against the Orioles.