For the second straight night, Eric Hosmer (hand) entered Friday's game as a defensive replacement.
Billy Butler hit a pinch-hit go-ahead two-run homer in a 6-4 win over the Indians on Friday night.
Aaron Crow worked a scoreless ninth inning Friday against the Indians for his second save of the season.
Yordano Ventura took a no-decision Friday after yielding four runs (three earned) over 6 1/3 innings against the Indians.
Salvador Perez went 3-for-4 with a solo homer and two runs scored Friday against the Indians.
Eric Hosmer entered Thursday's game as a defensive replacement.
Norichika Aoki helped the Royals walk off with an RBI single in Thursday's 14-inning, 2-1 win over the Indians.
Danny Duffy tossed seven shutout innings, but took a no-decision as the Royals needed 14 innings to earn victory from the Indians on Thursday.
Jason Vargas (appendectomy) will throw a simulated game on Saturday.
Royals manager Ned Yost said Thursday that Billy Butler will lose playing time in the designated hitter spot in the coming days.
Eric Hosmer (hand) will not swing a bat Thursday.
Danny Valencia (hand) finished 0-for-3 with a strikeout in his return to the Royals' lineup Wednesday.
Greg Holland collected his 26th save of the season Wednesday in the Royals' defeat of the White Sox.
James Shields held the White Sox to one run in seven innings Wednesday in a 2-1 Royals victory.
Eric Hosmer was pulled from Wednesday's game against the Cubs with "decreased grip strength in his hand."