Hector Santiago will not be available to pitch in Puerto Rico's showdown with the United States in Wednesday's World Baseball Classic final.
Phil Hughes was tagged for six runs -- five earned -- and nine hits in two innings by the Astros on Wednesday.
Drew Stubbs went 0-for-4 on Wednesday, lowering his spring average to .147 in 34 at-bats.
Twins purchased the contract of LHP Craig Breslow from Triple-A Rochester.
Twins placed RHP Trevor May on the 60-day disabled list with a right elbow injury.
Trevor May will undergo Tommy John surgery on Wednesday.
Twins released RHP Ryan Vogelsong; re-assigned RHPs Jake Reed and Raul Fernandez to minor league camp.
Kyle Gibson's strong spring continued Tuesday, as he allowed one run over five innings against the Phillies.
J.T. Chargois gave up two runs in two-thirds of an inning Tuesday, taking his spring ERA to 8.64.
The Twins will meet this week to come up with a plan for Glen Perkins (shoulder) moving forward.
Trevor May is expected to get a second opinion on his elbow on Tuesday.
Ryan O'Rourke (elbow) is expected to begin the year on the disabled list.
Eddie Rosario delivered a walk-off sacrifice fly in the 11th inning as Puerto Rico defeated the Netherlands 4-3 to advance to the World Baseball Classic championship game.
Tyler Duffey started and threw five scoreless innings Monday in the Twins' 8-2 win over the Blue Jays.
Adalberto Mejia surrendered a pair of solo homers over four innings of relief Monday against the Blue Jays.