Raul Alcantara was lit up for four homers and five runs in two-plus innings by the Mariners on Friday.
Danny Valencia (neck) was scratched from the Athletics starting lineup on Friday.
In addition to surgery on his left foot, Jed Lowrie also recently had an operation for a deviated septum.
Chad Pinder went 1-for-2 with a solo home run in Thursday's loss to the Mariners.
Kendall Graveman handcuffed the Mariners in Thursday's no-decision, yielding one run on seven hits over 5 2/3 innings.
In his return from the disabled list, Sonny Gray pitched a scoreless inning Wednesday against the Angels.
Marcus Semien hit his 27th homer Wednesday against the Angels.
Athletics activated RHP Sonny Gray from the 15-day disabled list.
Ryon Healy went 3-for-4 with an RBI double in Tuesday's loss to the Angels.
Daniel Mengden was demolished in Tuesday's loss to the Angels, yielding eight runs on nine hits over three-plus innings.
Sean Manaea held the Angels to one run and four hits over seven innings in a no-decision Monday.
Joe Wendle went 0-for-4 as Oakland's leadoff man in Monday's loss to the Angels.
Ryon Healy clobbered another home run on Sunday as the Athletics routed the Rangers 7-1 in Oakland.
Jharel Cotton earned his second victory of the season on Sunday, firing seven impressive innings of one-run baseball against the Rangers.
Sonny Gray (forearm) will start on Wednesday against the Angels.