Francisco Liriano was lit up for seven runs in 3 1/3 innings by the Mariners on Tuesday.
Gregory Polanco went 4-for-5 and hit his 13th homer Tuesday against the Mariners.
Ryan Vogelsong (eye) will make another rehab start Wednesday with Triple-A Indianapolis.
Josh Harrison is not in Tuesday's lineup against the Mariners.
Pirates optioned C Elias Diaz to Triple-A Indianapolis.
Pirates activated C Eric Fryer from the paternity leave list.
Jameson Taillon allowed four earned runs over six innings Sunday in a no-decision against the Phillies.
Pirates general manager Neal Huntington said Sunday that Tyler Glasnow's shoulder might have been bothering him before his start on Saturday.
Andrew McCutchen is not in the Pirates' lineup Sunday.
Pirates recalled RHP A.J. Schugel from Triple-A Indianapolis.
Pirates placed RHP Tyler Glasnow on the 15-day disabled list with a right shoulder injury.
Chad Kuhl left his start for Triple-A Indianapolis on Saturday with right biceps discomfort.
Mark Melancon picked up save No. 29 in the Pirates' 7-4 defeat of the Phillies on Saturday.
Tyler Glasnow was pulled from his second major league start Saturday due to shoulder discomfort.
Tyler Glasnow left his start Saturday against the Phillies with an apparent injury.