Roenis Elias' left elbow injury is not considered serious.
Fernando Rodney allowed one run in the ninth inning against the Angels on Thursday but hung on to earn his 46th save of the season.
Logan Morrison blasted a game-winning three-run homer in the top of the ninth inning to break a 0-0 tie and push the Mariners to a 3-1 win over the Angels on Thursday.
Felix Hernandez fired seven shutout innings, striking out 11, in a no-decision against the Angels on Thursday.
Taijuan Walker will start for the Mariners on Friday night against the Astros.
James Paxton worked 6 2/3 innings and allowed three runs in Wednesday's loss to the Angels.
Roenis Elias is scheduled to fly back to Seattle to undergo an MRI on his left elbow.
Dustin Ackley went 1-for-3 with a double and two RBI as the Mariners' stomped the Angels 13-2 on Tuesday.
Roenis Elias exited Tuesday's start against the Angels with left elbow stiffness.
Roenis Elias left Tuesday's start against the Angels with an undisclosed injury.
Hisashi Iwakuma was knocked around by the Angels on Monday, allowing seven runs on six hits across 3 1/3 innings.
Dustin Ackley is back in the Mariners' lineup Monday.
Austin Jackson went 2-for-5 with two stolen bases in Sunday's loss to the Athletics.
Chris Young allowed just two runs over six innings but took the loss against the Athletics Sunday.
Felix Hernandez yielded two runs in seven innings and struck out eight in a no-decision against the A's on Saturday.