Chris Heston was pounded by the Padres on Wednesday, allowing 11 hits and five runs over five innings of work in the loss.
Jake Peavy (back) could be cleared to begin a rehab assignment if he gets through another bullpen session on Friday with no issues.
Giants general manager Bobby Evans said in an interview on SiriusXM Wednesday that Hunter Pence (forearm) will need 7-10 rehab games.
Casey McGehee is not in the Giants' lineup Wednesday.
Buster Posey is not in the Giants' lineup Wednesday.
Angel Pagan (finger) is back in the Giants' lineup Wednesday.
Giants manager Bruce Bochy said Tuesday that Hunter Pence (forearm) could begin a rehab assignment within the next week.
Brandon Crawford reached base all four times he came to the plate, helping the Giants seal a 6-0 win against the Padres on Tuesday.
Joe Panik went 1-for-4 with a solo home run, helping the Giants emerge victorious over the Padres on Tuesday.
Ryan Vogelsong delivered seven scoreless innings to earn a win versus the Padres on Tuesday.
Angel Pagan has been scratched from Tuesday's lineup with a laceration on his left middle finger.
Casey McGehee is not in the starting lineup for Tuesday's game against the Padres.
Santiago Casilla worked a scoreless ninth inning for his eighth save as the Giants enjoyed a 2-0 win over the Padres on Monday.
Angel Pagan's RBI single in the third inning proved to be the only run the Giants would need in Monday's victory against the Padres.
Madison Bumgarner flirted with a no-hitter in Monday's win against the Padres, tossing 7 1/3 scoreless innings.